The Blog
Plain-spoken notes on
getting well.
Short reads from Dr. Pardue and the Vital Wellness team — on sleep, food, movement, peace, and what actually moves the labs.
- Your brain has a waste disposal system. Most people are unknowingly shutting it down.
It was only discovered in 2012. It clears the proteins linked to Alzheimer’s disease. And several common habits impair it every night. Until 2012, neuroscientists believed the brain had no system for clearing its own waste. Every other organ in the body uses the lymphatic system to remove cellular debris,
- The brain damage that shows up on MRIs before any symptoms
Vascular health and cognitive decline are more connected than most people realize — and it’s more reversible than you’d expect. Most people think of vascular health as a heart issue. Blood pressure, cholesterol, arteries — that’s cardiology territory. But your brain runs on blood flow just like every other organ
- July 1, 2026
- adamkuhn
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- The gene that matters most for Alzheimer’s risk.
One gene variant is the strongest known genetic risk factor for Alzheimer’s. Here’s what it means — and what you can do about it. There’s a gene that researchers now consider the single strongest genetic risk factor for late-onset Alzheimer’s disease. It’s called APOE — apolipoprotein E. Most people have
- June 23, 2026
- adamkuhn
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- Most people trying to protect their brain health are doing it alone.
A major JAMA study compared structured coaching to self-guided lifestyle change for cognitive protection. The results weren’t close. In July 2025, the U.S. POINTER study published its results in JAMA — the Journal of the American Medical Association. POINTER was a two-year, multi-site clinical trial testing lifestyle interventions in older
- June 15, 2026
- adamkuhn
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- The dementia risk factor hiding in plain sight
The world’s leading dementia research commission ranks hearing loss among the largest modifiable risk factors. In 2024, the Lancet Commission on Dementia Prevention, Intervention, and Care — the most authoritative ongoing review of dementia science in the world — published its latest report identifying 14 modifiable risk factors that together
- June 8, 2026
- adamkuhn
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